Clinical Data

Results from HeartFlow’s first multicenter study (DISCOVER-FLOW) were published in the Journal of the American College of Cardiology (JACC) in November 2011. DISCOVER-FLOW was a prospective multicenter study to determine the diagnostic performance of FFR_CT compared to measured FFR at the time of invasive coronary angiography (ICA) in patients with suspected or known coronary artery disease (CAD). FFR_CT was performed on 159 vessels in 103 patients undergoing coronary CT scans, invasive angiography, and measurement of FFR.

FFR_CT led to a 70% reduction in false positives and 42% improvement in per-vessel diagnostic accuracy when compared to CCTA. For more information, please click the thumbnails below.

FFR vs. CT and FFR_CT

Diagnostic Performance
of FFR_CT and CCTA

Patients and Lesions

Invasive FFR vs. Non-invasive FFR_CT

Koo, Bon-Kwon. Diagnosis of Ischemia-Causing Stenoses Obtained via Non-Invasive Fractional Flow Reserve (DISCOVER-FLOW): a Prospective MultiCentre First-in-Man Study. EuroPCR 2011.

Clinical Data

FFR vs. CT and FFRCT

Diagnostic Performance of FFRCT and CCTA

Patients and Lesions

Invasive FFR vs. Non-invasive FFRCT

FFR vs. CT and FFR_CT

Diagnostic Performance
of FFR_CT and CCTA

Invasive FFR vs. Non-invasive FFR_CT